I was prescribed a treatment regimen of 1 injection daily for 7 days, 1 injection every week for three weeks, and then 1 injection every month for three months. I was fine until I took the shot, afterwards, it had caused mental changes as well as mood changes. Your haematology results are not 'just' normal; they're very normal indeed. Because vitamin B-12 is water soluble and lipotropic components are safe, you dont have to worry about getting too much. Also, the needle needs to be long enough to reach the muscle of the person youre injecting. Mild diarrhea and/or upset stomach. I guess that your sharing of this article is to make the point that B12 deficiency may have a cause other than pernicious anemia. My GI said that I can only have it every 3 months, I cannot have it any sooner (thats the NHS for you). Felt very dizzy and sick from around 20 mins after having the jab and then just extreame exhustion. Then I got a cold and I havent been the same since. WebMD does not provide medical advice, diagnosis or treatment. A very different experience to the loading doses. Necessary cookies are absolutely essential for the website to function properly. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Might be worth posting your update in a new thread as responses on older threads sometimes get missed. ), and I could tell he was really healing at six months. I have a day where I feel ok and then a day where everything seems to start up again. Any advice is appreciated. Has anyone else felt this way? To make sure your B12 is free of any additives, you may want to try a vial of our pure methyl B12. What size needle do you need for B12 injection? Key facts. It seems it will be a while yet until I will feel 100%. Where is the best place to give a B12 injection? PA testing only picks up 50% of yhise with it. Product is costly when purchased with prescription. So am still not feeling great and was hoping the B12 would improve it. Hypophosphatemia after an iron infusion is quite rare. Some people can get a drop in potassium levels (hypokalaemia) when they start B12 treatment. Always speak to your doctor before acting and in cases of emergency seek because obviously b12 medications are being used as a mere bandaid , 20yrs for some of you? Id be interested to know how you get on. Had 3 injections per week from physician for 2 months, continuing to take 1cc injections IM per week at home. I'm aware of that - I do not have PA myself but had a B12 deficiency. However, you may need them more or less often. There may have been other things in the mix such as Iron etc, but its highly unlikely there's a B6 toxicity issue. So, it's more noticable? a 89 year old lady developed signs of malaise, collapse and vomiting. i will post further progress with this drug as my treatment furthers with it. I have MTHFR mutation and wonder if this might be why they are not having a good effect on me. After 9 months of feeling completely not myself, test for all sorts of different things plus fighting the " your symptomsare anxiety" card I was finally diagnosed with Coelliac disease and the the B12. i know that your question is 4yrs old and i hope youve found the answer if not , latest findings on B6 toxicity does seem to match most of your symptoms. This website uses cookies to improve your experience while you navigate through the website. I don't doubt in the least that juanpablo is suffering from something, but I'd be surprised if B12 had anything to do with it. This time I felt anxious for about 10 mins that evening, tired and achy the next day, but that has been it. Can give similar symptoms to low B12, you might be deficient in both. I could be wrong but I'm gonna guess you're not devouring enormous quantities of liver, beans and lentils? If you search online for "Sally Pacholok B12 conference" it should show a link to a slideshow Sally presented to a conference in US. i highly recommend vitamin b12, I have other medical conditions, and I went to a lab place to receive one to get an increase in my energy level. Vitamin B-12 is a water-soluble B complex vitamin found naturally in a variety of foods, including meat, fish and dairy products. The only difference I noticed is that my nerve endings have been more active. That will take a good six months to one year - even longer in some. Also I was severely iron dificient. Dont store them inside a kitchen cabinet or the refrigerator. I wouldn't want either and I feel for you with both As mentioned already, CD can go with other conditions such as thyroid, PA (low b12 can be fixed, PA requires ongoing supplements/treatment), even type 1 diabetes and other auto-immune conditions. You can change your diet to include vitamin B12-fortified grains, a supplement or B12 injections, or a high-dose oral vitamin B12 if you are deficient. He saw an improvement upon starting the treatment. I began B-12 injections 2 times per week and within one week noticed a dramatic improvement in my energy levels. Though rare, this reaction can cause muscle cramping, extreme fatigue, and an irregular heartbeat. No negative side effects, however I am taking this in addition to a progesterone supplement due to earl. Like it needs to be sorted because its affecting my everyday life. Considering the number of injected patients and the amount of reported cases, you get the idea how rare reactions really are. Hi Quinny99 I was wondering if you felt any better since your last post. And please, stay away from cyanocobalamin. Older adults who have a vitamin B12 deficiency will likely have to take a daily B12 supplement or a multivitamin that contains B12. cystic acne breakouts by a dermatologist. Patient does not provide medical advice, diagnosis or treatment. No prescription needed. That means any excess is quickly flushed out through the urine. These results are really 'quite strange'. Saliva: Edibles can be detected in saliva for 1 to 3 days. I was told my energy level would increase and B12 would help prevent dementia. If B12 blood levels and MMA are both high, a functional B12 deficiency could be preventing B12 being useful at cell/tissue level. Theres no solid evidence that vitamin B-12 injections aid weight loss. I cant do much until I have some sort of diagnosis so I can sort myself out. But adverse effects are recorded in a way that necessitates their inclusion as B12 injection symptoms as well. Our injectable B12 is methylcobalamin, which is an active, native form with no recorded anaphylactic reactions in medical literature. I am going back to review my labs in person soon with my GP and not sure the approach I should take on how to convince him to check other things and what other things should be looked at. Generalized pain, including arthritis, back pain and muscle pain may occur after a vitamin B12 injection. respect of any healthcare matters. Recently, vitamin B12 injections and infusions have become popular among healthy people who dont appear to have a deficiency. Advocates of this approach claim that regular injections can boost energy levels and help with weight loss and mood. However, there is little to no evidence to support these claims. That's in millions of results. However, sometimes they can indicate something more serious, like an infection or allergic I was prescribed a treatment regimen of 1 injection daily for 7 days, 1 injection every week for three weeks, and then 1 injection every month for three months. I have had crying episodes that I did not have beforeso this vitamin injection did me little good. I? Im just hoping that this injection will make me better. For me it took until the last jab until I felt better . Now I feel like I did in my 20's. Who can and cannot have it Having your injection Side effects Pregnancy, breastfeeding and fertility Having it with other medicines and herbal supplements Common questions Related conditions. Skip dairy for now, or take lactase supplements. Routine test showed a B12 deficiency that was unreadable by local labs. If I have any of this wrong, feel free to correct me (addressing more experienced members of this forum). If you order your B12 shots anywhere else, make sure it comes from a certified lab that follows stringent pharmacy regulations. Store the vials in a cool room. B12 tablets, probiotics, etc. If you can get to see a doctor please also ask him/her to re- check your Folate level as this and B12 help your iron to make red blood cells and to function properly. Everyone's different, but it is a rollercoaster ride and what you're saying is "normal" for either or both conditions. However, its important to know what your levels are, after all, vitamin B12 deficiency can cause damage to your nerves and affect brain function. My doctor recommended these injections as I've gone 100% vegan diet about a year ago. WebThis causes symptoms like muscle weakness, fatigue, appetite loss, feelings of unwellness, irritability, numbness, etc. Pretreatment with acetaminophen or NSAIDs and H1 inhibitors will often help the discomfort and many physicians add systemic corticosteroid prior to the infusion if symptoms persist. Whether its a mild rash, a cut, or an eczema flare irritated skin is inflamed and more likely to have a reaction. How long does 600mg edible last in your system? Almost immediately, I developed swollen, painful sores that were identified as cystic acne breakouts by a dermatologist. My son was a different person within 4 months (had 2nd worst category of villus atrophy so he was young but far gone at age 6! Nitric oxide is a gas we make , Blood: THC from edibles can be detected for 3 to 4 days in blood. Symptoms I had after loading were spots everywhere , dizziness, nausea and fogginess in head which were all more extreme than before loading. Brace yourself for the worst right now, but know that each jab and each GF day is making you better! There is no set timescale as we are all different. Allergic reactions to proprietary preparations of vitamin B12 might be due to substances added to the solutions as preservatives or for other reasons, to impurities from the production, or to the vitamin B12 itself. Now I However, certain people are at an elevated risk. But I feel like I could try it in the next couple of weeks. Not a single case. Product is costly when purchased with prescription. I have B6 toxicity, P.A. Certainly helped me to know that, though,by ruling out anything more serious. weekly vitamin B12 shots and after the first I felt great. It just goes to show that the 'B12 deficiency is unlikely in someone so young' is probably right most of the time, but not always. What you describe isn't quite the same as '0', is it? Neurological damage from B12 deficiency is very slow to heal, often imperfectly healed and if not treated in time, may be permanent to at least some degree. Did your daughter have any abnormal hematology results? The easiest site when self-administering an IM injection is the middle third of the vastus lateralis muscle of the thigh. Hypophosphatemia is one of the reasons patients complain about still feeling tired after iron infusions and are feeling worse after iron infusion. What is the fastest way to fix B-12 deficiency? I heard that u can feel worse after injections for a while then it improves which i really hope it does i just want to be back to full energy like i was a few days after injections. Vitamin B12 injections side effects are remarkably rare. We also use third-party cookies that help us analyze and understand how you use this website. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Free worldwide shipping. It is a synthetic form of B12 that contains cyanide attached to the B12. Read our editorial policy. You'll likely feel rubbish for the next few jabs. Im experiencing exactly the same as you. Good luck and I wish you well on your recovery xxx. Cited by 25 Although measurement of vitamin B12 levels is the gold standard for the diagnosis of B12 deficiency some reports do exist concerning difficulties in its assay. I can appreciate the reasoning for not doing a B12 assay when checking her ferritin [or whatever iron indicator] but checking B12, Folate and Ferritin at the outset is probably wisest. My daughter feels so much better now. Try our Symptom Checker Got any other symptoms? Vitamin B12 or folate deficiency anaemia can cause a wide range of symptoms. I'm on loading injections and feeling worse, Hi how are you feeling now.. just reading all these threads and it sounds like what I'm going through now, Hi Quinny99, Did something helped with your symptoms. People with digestive issues or celiac disease may not be able to process and absorb B12. What Is The Difference Between 'Active Vitamin B12' and 'Total Vitamin B12'? Do you keep B12 injections in the fridge? A few symptoms of B12 deficiency include: Conditions of the small intestine (Crohns disease), anemia, fatigue, constipation, poor balance, memory loss, shortness of breath, and more. Rhinitis (chronic sneezing or a congested, drippy nose). Had 3 injections per week from physician for 2 months, continuing to take 1cc injections IM per week at home. Posted With either of those alone, your mood could be affected, your balance, memory, nerves, hearing, etc. My migraine is gone and has not returned thankfully, but still dealing with heart palpitations, fatigue, anxiety attacks, and inability to focus. The paper they provide mentions one report of peripheral neuropathy associated with 8.7mg of B6. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Injection site reactions are usually mild when they do occur. Vitamin B12 As a general rule of thumb, take your B vitamins in the morning or with a meal. Women with a history of infertility or multiple miscarriages. I may not be postulating this right, but the \ B12 and B9 are so inter-related. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. But I havent had a diagnosis of anything yet, and theyre still insisting its my diet, when I 100% know its not. If it is high, it might be worth seeing what your methylmalonic acid (MMA) is doing. I felt better overall each week, but my symptoms still ebbed and flowed for a while. I started B12 injections in March 2009 monthly. Read our pernicious anemia diet page for more advice. Thank you again. Ive been to a few and none of them can tell me anything. Is vitamin B12 good for energy? This is because it is important for energy metabolism, which may interrupt your sleep if taken at night. I'm in UK and I've had some very difficult experiences with doctors in UK. What is the relation between b12 deficiency and weight gain? The cookie is used to store the user consent for the cookies in the category "Performance". If its none of the things hes testing, he said its probably anxiety. For subcutaneous injections, pinch the fat and insert the needle into the fat under the skin. Hydroxocobalamin is usually the recommended option as it stays in the body for longer. We scoured the medical database looking for allergic reactions to B12 shots, and this is all we could find. You could be low in iron now. You're right Technoid. I just need to sort myself out as its stopping me from going to University lectures and stuff like that. So I was wondering if theres any conditions that may affect this? Whatever the results, the complaint remains- the reason for juanpablo111 's initial visit to the walk-in clinic. Additionally, it's important to drink plenty of water before and after your injection in order to flush out any toxins that may have built up in your system as a result of the shot. PearlH -- not sure if you'll see this, but B6 lowers FOLATE. Many people experience this issue, yet it is often misunderstood. It's not always the case, but I would have expected something as well as an unmeasurable B12. I've never seen B12 listed as a cure for eczema but if it wasn't what cured her skin issues it was awfully coincidental. I never read on the B-12 shot, but I received it yesterday at,12:30 pm and around 5 this morning I started with belly pain and diarrhea. They don't even hurt. So Im about to go for my first injection (as I have them once every 3 months). I will update and let you know how I get on. But everyone reacts to everything differently. My sister feels like I complain too much, but she's not in our shoes and she wants sympathy-likes on FB if she's got a hangnail. B12 may be injected into a muscle or under the skin at 100 mcg daily for a week, every other day for another week, and then every three or four days for a month. Although I have discovered that my experience is not necessarily unique, it is also not that common. Fortified foods? Other options include the deltoid muscle of the upper arm and the dorsogluteal site on the bottom. I get tired and short tempered. Tingling, numbness, weakness, and balance problems. The light finally comes on and I take my shot. Some symptoms will "disappear" quite quickly whereas others may take months or even years. BE CAREFUL with any supplement/vitamin you take! I have heard of people being told on this forum that their results were "below measurable" -but never that they were non-existant ! Been taking this when B12 levels were below 120. Someone once described it to me as the nerves starting to wake up after being starved of B12 for so long. Has some overseas members. WebI began B-12 injections 2 times per week and within one week noticed a dramatic improvement in my energy levels. I was found to have "ventricular ectopics" - which, although I had 4,000 episodes in that period, was not dangerous and went away eventually a few months later without needing treatment. I'm not medically trained just someone who suffered for years from unrecognised and untreated B12 deficiency. Typically, our patients experience positive effects between 24-72 hours after the treatment. I suffered extreme fatigue, tingling lips, fingers and just a general lack of lust for life. Most weight loss patients only need about one weekly injection. Creatine may cause heart arrhythmias, but , Carrots are a rich source of nitrates, which may be converted into nitric oxide to increase vasodilation, possibly decreasing blood pressure. Avoid irritated skin and blood vessels. It's now impossible to say whether that was true, or a placebo effect. Eating bananas and trying a very healthy diet but the increase of symptoms and pain make me very, very insecure and scared. The nurse seems to think its unusual to feel worse after an injection but I've now had 3 and the more pronounced. The cookie is used to store the user consent for the cookies in the category "Other. Sadly my much improved digestion has gone downhill again. If youre injecting a premature newborn, avoid benzyl alcohol at all cost due to the risk of gasping syndrome. Hi Quinny99 - how are you feeling now?I experience a huge spike in symptoms after an injection too. What is the , It raises the risk for heart disease, cancer, liver damage, and stroke. People with a family history of pernicious anaemia. Was she anaemic? So Im sure you will get there. Character (stabbing,burning,very deep?? But, it feels equally bad while that happens (my experience, too) or maybe worse. Stuart (US authors). It can lead to paralysis, dementia, psychosis, and permanent and irreversible damage. I haven't felt much of a change in my migraines, but have noticed that I just haven't been feeling well overall on a day to day basis. I need to be ok for my kids . My guess still remains that there's been an error in the process somewhere and it's 'crept out'. It will take time but one year from now you will be soooo sosososo much better! I was fine until I took the shot, afterwards, it had caused mental changes as well as mood changes. Had b12 low was on injections and had h pylori. i know that your question is 4yrs old and i hope youve found the answer if not , latest findings on B6 toxicity does seem to match most of your symptoms. B12 is water-soluble, and its generally safe even at very high doses. Anaphylactic reactions (strong allergic reactions) have been reported, though very rarely, to either cyanocobalamin, hydroxocobalamin, or both: Allergy to vitamin B12 is uncommon. Its interesting how many people do not instantly feel better from the B12 loading doses. My current experience is not great, unless you can define nausea as "great." This includes the nerve cells(neurons) of the brain. I have been battling migraines for two+ decades. Based in Wales, UK. Without sufficient B12, nerves become exposed and are easily damaged resulting in sensory and motor dysfunction. Typically, 'less than 50' might be a response, depending on the method used and the laboratory. Major confusion, depression, and fatigue. My symptoms are headaches, sensitive eyes, strange smells, metalic taste in my mouth, severe neck ache, a hard to discribe numb feeling in my chest, pins and needs How are you managing things now, Diagnosis with PA a month ago & had my 6 loading injections last one last week, Feel awful too , worse my b12 was 150 & serum iron 8, Also now started, really hope things improve soon. Vitamin B12, for example, should definitely be taken in the morning. But opting out of some of these cookies may affect your browsing experience. Anemia, when you don't have enough red blood cells. There is a complex interaction between folic acid, vitamin B12 and iron. The opportunity has gone. People with Crohns disease, irritable bowel syndrome, gluten enteropathy (celiac disease), or any other disease that cause malabsorption of nutrients. According to the medical site Drug3K, B12 injections should be stored at a stable temperature of between 59 and 86 degrees Fahrenheit. These cookies ensure basic functionalities and security features of the website, anonymously. The Many Faces of Cobalamin (Vitamin B12) Deficiency. Any supplementation? That was big for me, and it's how I found this site in the first place (I'm in the US). y in life hysterectomy. Recently I? If you reacted to B12 shots in the past (if it had anything to do with the shots at all), the cause was likely not the B12, but some troublesome excipient in the mix. My symptoms are headaches, sensitive eyes, strange smells, metalic taste in my mouth, severe neck ache, a hard to discribe numb feeling in my chest, pins and needs in my hands (mainly left) numbness in my 4th toe (also left sided), weak heavy leg feeling like I'm about to faint,difficulty stringing a sentance together, forgetting memorable words, losing track of what I'm saying mid conversation, clumsy hands and poor spacial awareness (always hiting my hands on things) cold hands and feet, dizziness and ppor balancethe list goes on.. It's truly huge agony, all the pain, the neurological symptoms, the brain fog, tingling, headaches, fatigue and so onreading stories here do reassure me though that is due to the healing process, so we must keep the faithFeeling scared and insecure about the symptoms bothers me the most, because docs say it is highly unusual to feel the way I do :/ But like I said, they often don't care and not aware of what is really going on. this seems to be quit good, has good results already, and is easy to tak. If you get the blood results Im sure that will help. After the jabs I had like one month where I felt great, like I could go out running and Id be fine. I was on prescribed folate but when that finished I now take a multi vitamin every day . I have other medical conditions, and I went to a lab place to receive one to get an increase in my energy level. Vegetarians or vegans will not be getting sufficient B12 in their diets. For most people it is the best form. I hope you are feeling better now and things are starting to settle down for you x x x. I am 40 years old and was tired all of the time. Put simply, I don't believe the B12 result, and in my lab, I never saw a result of zero for B12. This will help your body adjust to the increased levels of B12 without having an adverse reaction. Clinics charge as much as $250 per B12 shot. I could go out jogging and I felt great. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Thanks to its role in energy metabolism, vitamin B12 might reduce your chance of fatigue. I do hope you get to the bottom of this. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. IMO might be worth encouraging the doctor to query the lab as to exactly what happened there. For them, it can make things worse. After having the loading doses just over a year ago , I thought the doctor had got it completely wrong and they were trying to kill me . I feel dizzy, sick, really cold hands, numbness in my hands and a very spaced out almost migrainey type feeling. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. B12 is a water-soluble vitamin. Patient is a UK registered trade mark. But Im just not well all the time, constantly in pain. Hi, I still get foot cramps and I have numbness in my left leg and left hand. I am not saying that this is an easy thing to do but try to stay calm, write out what you want to say and keep to the script and be confident that you are "in the right" and your facts are correct. A lot will depend on the severity and longevity of your B12 deficiency as to how long before there is no further improvement or recovery. Older adults and people with digestive tract conditions that affect absorption of nutrients also are susceptible to vitamin B-12 deficiency. Muscle imbalances. It's extremely unlikely such symptoms are B6 related. Ihave recently been diagnosed with B12 deficiency and commenced my loading dose injections yesterday. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Folic acid works closely with vitamin B12 in making red blood cells and helps iron function properly in the body and your B12 levels were below the bottom of the range. Lifestyle factors such as heavy smoking and drinking or a poor diet over a prolonged period can also lead to low B12 levels or deficiency. Thank you so much!! This is great and I will continue the shots without question. Contact PAS for details. Youre not alone. We have many repeat customers, so it must tell you something about how rare a true allergy is. WebThe most common cause of vitamin B12 deficiency in the UK is pernicious anaemia, which is not related to your diet. If anything other than sterile saline was added, it may have been a preservative that you had reacted to. If youre sure the B12 was pure, then the next question would be, was the correct fluid added to the vial? My right toe has residual numbness. But I had my 6th on Hello! It's important to stick to your b12 schedule . Vitamin B12 or folate deficiency Overdosing with B12 is not very likely, yet too frequent administration may cause side effects like nausea, skin swelling and redness (on the injected spot), and similar. i take vitamin b12 injection it has helped me tomaintain my weight & help termendously with stress. People whove undergone any gastric and/or intestinal surgery, including bariatric surgery for weight loss purposes (Gastric bypass). Keep in mind when I got the ECG I was having a severe panic attack and had a heart rate of around 110 so not sure if this tachycardia caused by anxiety resulted in this assessment (I think it's an automated assessment from the machine) . So Im still not well thinking I may need iron ? not moderated or reviewed by doctors and so you should not rely on opinions or advice given by other users in When mine suddenly got worse, day and night, I was fitted with a heart monitor for 24 hours. The cookies is used to store the user consent for the cookies in the category "Necessary". I tend to get over excited at the thought of feeling better which then makes the disappintment when it doesnt happen much worse. Its a pain being in pain all the time! the injection that they gave me has vitamin B-12, methione, inositol, and choline in it and was referred to as vitamin B-12 and MIC shot.

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